Search on:
CYTOCHROME P4501B1
Descriptors Found:
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DeCS
Descriptor
English
:
Cytochrome P-450 CYP1B1
Descriptor
Spanish
:
Citocromo P-450 CYP1B1
Descriptor
Portuguese
:
Citocromo P-450 CYP1B1
Synonyms
English
:
Cytochrome P450 CYP1B1
Cytochrome P450, Family 1, Subfamily B, Polypeptide 1
Cytochrome P4501B1
Cytochrome P 450 CYP1B1
P450 CYP1B1, Cytochrome
Tree Number:
D08.244.453.005.500
D08.244.453.100.875
D08.811.682.690.708.170.010.500
D08.811.682.690.708.170.020.875
D12.776.422.220.453.010.500
D12.776.422.220.453.100.875
Definition
English
:
A
cytochrome
P450 aryl hydrocarbon hydroxylase that has specificity for
ESTROGENS
which it converts into 4-hydroxy
estrogens
. CYP1B1 has been shown to be physiologically important for
FETAL DEVELOPMENT
with
mutations
in the CYP1B1 gene resulting in congenital forms of
GLAUCOMA
and Peter's anomaly.
Indexing Annotation
English
:
/antag: coordinate with
CYTOCHROME P-450 ENZYME INHIBITORS
History Note
English
:
2015
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
55605
Unique Identifier:
D065633
Occurrence in VHL
:
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